Sks lrat. LRAT is encoded by this gene is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester, an essential reaction for the retinoid cycle in visual system and vitamin A status in liver. Mutations in this gene have been associated with early-onset severe retinal dystrophy. [provided by RefSeq]
The SKS shoots the same 7.62×39 round as the AK-47/AKM family of firearms, but is perhaps less widespread. Not to say that the SKS rifle isn't a reliable option, but it hasn't earned the same ...
Purpose. The Rpe65 −/− mouse, used as a model for Leber congenital amaurosis, has slow rod degeneration and rapid cone loss, presumably due to the mistrafficking of cone opsins. This animal does not generate 11-cis retinal and both the loss of cones and the rod response are restored by 11-cis retinal administration.The Lrat −/− mouse likewise does not produce 11-cis retinal.
The 5.3 kb LRAT transcript was predominant in the liver of retinoic acid-repleted vitamin A-deficient rats, coincident with increased quantitative expression of LRAT mRNA and enzyme activity. The differential usage of these polyadenylation signals can explain the presence of multiple LRAT mRNA transcripts which are expressed in different tissue ...LRAT expression was increased at 6 h by all treatments, in the order VA < at-RA = VARA << Am580 and VAAm580 (Fig. 5). By 12 h, LRAT mRNA was reduced toward basal levels in the VA group and had fallen entirely to or somewhat below basal levels in the lungs of RA and VARA-treated neonates. By comparison with RA, Am580 dramatically increased …
Target Information. Lecithin retinol acyltransferase (LRAT) is a membrane bound enzyme that catalyzes the transfer of an acyl group from the sn-1 position of lecithin to vitamin A which generates all-trans-retinyl esters (tREs) in the liver, some extrahepatic tissues, such as the lung, and retinal pigmented epithelium.Search the Guns.com database to shop for guns, ammo, mags, optics and more. Filter products to compare by specs and price. New and certified used handguns, shotguns, rifles...Yugoslavian SKS M59/66 Barrel. New Old Stock condition. No gas port drilled. Would make a good replacement for your rifle. Will only work for the M59/66 models. Completely chambered in 7.62x39. Would .. $60.00 . Add to Cart. Yugoslavian SKS M59/66 Bayonet Collar - NOS Condition ...Lecithin retinol acyltransferase (LRAT; EC 2.3.1.135) catalyzes the first of a series of reactions that take place in retinal pigment epithelium (RPE), by which the chromophore of the visual pigments, 11-cis retinal, is derived from vitamin A (all-trans-retinol).Most LRAT missense mutations associated with retinal degeneration are localized within the catalytic domain, whereas E14L substitution is localized in an N-terminal α-helix, which has been implicated in interaction with the phospholipid bilayer. To elucidate the biochemical consequences of this mutation, we determined LRAT(E14L)'s enzymatic ...Mechanisms of ER Stress in Retinal Disease. Sylvia B. Smith, in Retina (Fifth Edition), 2013 LRAT mutations. An inherited retinal dystrophy that preferentially affects cones before rods is Leber congenital amaurosis (LCA), the most severe retinal dystrophy in early childhood. 21 Mutations in RPE65 or lecithin-retinol acyltransferase (LRAT) disrupt 11-cis-retinal recycling, causing this ...The SKS rifle is a Soviet-designed semi-automatic carbine that entered widespread service in the late 1940s. It was produced by several nations and saw extensive combat use in Vietnam, where it was prized for its durability, accuracy, and firepower. Although it has been replaced by more modern firearms in most militaries, the SKS remains ...May 13, 2024 by William Taylor. The SKS and AK-47, both popular firearms, have some key differences. The SKS is a semi-automatic carbine with a fixed magazine, while the AK-47 is a selective fire assault rifle with a detachable magazine. Contents [ show]This SKS replacement stock has the recognizable and appealing design of a Dragunov rifle. The durable material is due to its immunity from physical changes that can be induced by humidity and unfavorable weather. Additionally, it is strong and easy to travel with, weighing only 2 lb. 7 oz. (1.11 kg).However, in the short run you can increase the utilisation of existing factors of production, e.g. workers doing overtime. In the short run, an increase in the price of goods encourages firms to take on more workers, pay slightly higher wages and produce more. Thus the SRAS suggests an increase in prices leads to a temporary increase in output ...
LRAT plays a critical role in vision (Probable). It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium.due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the ...Lecithin retinol acyltransferase (LRAT) 1 is a transmembrane protein that forms retinyl esters in a variety of tissues (1–4).In some cells, retinyl esters are thought to be a storage form of all-trans-retinol (Vitamin A).These esters are hydrolyzed by retinyl ester esterases when there is a need for conversion of retinol to one or another of its retinoid …SWIFT Code SKSBRUMMXXX Breakdown SWIFT Digits: 8 - The short 8-letter swift refers to the PRIMARY Office of SKS BANK, LLC, MOSCOW. Institution / Bank Code: SKSB - This is the institution / bank code assigned to SKS BANK, LLC, MOSCOW. Country Code: RU - This is the 2-letter country code associated with RUSSIAN FEDERATION (RU). Location Code: MM - This represents the location code, and the ...Lecithin:retinol acyltransferase (LRAT), present in microsomes, catalyzes the transfer of the sn-1 fatty acid of phosphatidylcholine to retinol bound to a cellular retinol-binding protein.In the present study we have cloned mouse and rat liver LRAT cDNA and tested the hypothesis that LRAT mRNA, like LRAT activity, is regulated physiologically in a liver-specific manner.
Yugo SKS or AK Brass Oil Bottle and Brown/Natural Leather Pouch. $19.95. Add to Wish List. Add To Cart. SKS 7.62x39 Rifle Parts for sale. Hard to find original SKS rifle parts for your Russian, Chinese, Romanian, Polish, and other variants. Parts include gas tubes, handguards, bolts and carriers, pistons and other quality parts for you to buy ...
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Kit includes 5 LRAT-2000 LinkRunners and 5 LinkRunner AT Mobility Kits which includes auto charger and a holster for each mobility kit. Discontinued! This product has been discontinued and is no longer available.The H-RAS-like suppressor (HRASLS) subfamily consists of five enzymes (1-5) in humans and three (1, 3, and 5) in mice and rats that share sequence homology with lecithin:retinol acyltransferase (LRAT). All HRASLS family members possess in vitro phospholipid metabolizing abilities including phospholipase A 1/2 (PLA 1/2) activities and O ...Boyar Research President Jonathan Boyar joins Yahoo Finance Live to discuss top stock picks, the U.S. banking crisis, rate hikes, and the outlook for investors. Boyar Research Pres...Here's The Deal On This Shipment. These are the same Chinese SKS rifles that we sell by the individual rifle except we are offering them to you as a 20 piece crate With each crate, we are throwing in 20 new slings, 20 surplus oil bottles and 20 surplus ammo pouches all for the price of $6200. How cool is that!
SKS ejection patterns and optics mounting: The SKS rifle is designed to eject empty shells at between 1 to 2 o'clock. However, due to gas pressure and/or shells bouncing in the receiver wall. It is not rare that an SKS throws shells at 12 o'clock, and may hit the optic if it is mounted backwards or too high.Ø Lrat-201 gene has 2 exons, with the ATG start codon in exon1 and TAG stop codon in exon2. Ø We make Lrat-P2A-iCre knockin mice via CRISPR/Cas9 system. Cas9 mRNA, sgRNA and donor will be co-injected into zygotes. sgRNA direct Cas9 endonuclease cleavage near start coding(ATG) of Lrat gene, and create a DSB(double-strand break).Lecithin-retinol acyltransferase (LRAT), an enzyme present mainly in the retinal pigmented epithelial cells and liver, converts all-trans-retinol into all-trans-retinyl esters. In the retinal pigmented epithelium, LRAT plays a key role in the retinoid cycle, a two-cell recycling system that replenis …A novel LRAT mutation affecting splicing in a family with early onset retinitis pigmentosa. Chen Y, et al.Hum Genomics, 2018 Jul 4. PMID 29973277, Free PMC Article A novel homozygous mutation causing lecithin-cholesterol acyltransferase deficiency in a proband of Romanian origin with a record of extreme gestational hyperlipidemia.Lecithin:retinol acyltransferase (LRAT), present in microsomes, catalyzes the transfer of the sn-1 fatty acid of phosphatidylcholine to retinol bound to a cellular retinol-binding protein. In the present study we have cloned mouse and rat liver LRAT cDNA and tested the hypothesis that LRAT mRNA, lik …We would like to show you a description here but the site won't allow us.AMMO INC M67 7.62X39 BRASS CASED 123GR FMJ, 180RD CAN. Price $124.99. STRIKEFORCE TACLITE SKS STOCK KIT, GRAY. Price $114.95. STRIKEFORCE TACLITE SKS STOCK KIT, FDE. Price $114.95. STRIKEFORCE TACLITE SKS STOCK KIT, BLACK.An SKS typically shoots a 7.62x39mm caliber bullet. Contents What is the effective range of an SKS? The effective range of an SKS is generally considered to be around 400-500 yards. What is the magazine capacity of an SKS? The standard magazine capacity of an SKS is 10 rounds, but extended magazines are also available. ...Result of Lrat Cre-driven expression of mutant gain-of-function NLRP3 on hepatic stellate cell phenotype Western blot of whole liver lysates showed augmented Nlrp3 inflammasome-related proteins in Nlrp3 L351P/+ Lrat Cre mice (A), supported by quantification of protein levels of NLRP3, Caspase1 and IL-1β (B) as well as elevated mRNA levels of ...Analysis of the 3' ends of LRAT mRNA transcripts from liver, intestine and testis showed the usage of both canonical and non-canonical polyadenylation signals. To further analyse the LRAT mRNAs expressed in vivo, Northern blot analysis was performed using four probes spanning sections from the 5' end to the distal 3' end of the 5.3 kb …Abstract. Cellular uptake of vitamin A, production of visual chromophore and triglyceride homeostasis in adipocytes depend on two representatives of the vertebrate N1pC/P60 protein family, lecithin:retinol acyltransferase (LRAT) and HRAS-like tumor suppressor 3 (HRASLS3). Both proteins function as lipid-metabolizing enzymes but differ in their ...The Simonov SKS semi-automatic rifle was designed in Russia 1946, but eventually was replaced by the AK-47 assault rifle. Some SKS rifles were modified later to accept AK magazines. The Norinco SKS is a Chinese variant, some of which accept AK magazines while others do not. The AK magazines hold more rounds than the ...Two Models: LRAT-2000 and LRAT-1000 LinkRunner AT is available in two models: LRAT-2000 and LRAT-1000. LinkRunner AT 2000 adds the following exclusive features: • Fiber support* • TruePower™ PoE Power - test up to 30W* • IPv6 support* • Reflector support* • More result storage: 50 instead of 10* • Uses Li-ION rechargeable battery ...LRAT has a role in retinoid absorption and storage. analysis of the topology and subcellular localization of LRAT, a critical enzyme in vitamin A metabolism. Enables phosphatidylcholine-retinol O-acyltransferase activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation ...Background: Leber congenital amaurosis, caused by mutations in RPE65 and LRAT, is a severe form of inherited retinal degeneration leading to blindness. We aimed to assess replacement of the missing chromophore 11-cis retinal with oral QLT091001 (synthetic 9-cis-retinyl acetate) in these patients.LRATD2 (LRAT Domain Containing 2) is a Protein Coding gene. Diseases associated with LRATD2 include Breast Cancer. An important paralog of this gene is LRATD1. Additional gene information for LRATD2 Gene. HGNC (24166) NCBI Gene (157638) Ensembl (ENSG00000168672) OMIM® (609483)Most LRAT missense mutations associated with retinal degeneration are localized within the catalytic domain, whereas E14L substitution is localized in an N-terminal α-helix, which has been implicated in interaction with the phospholipid bilayer. To elucidate the biochemical consequences of this mutation, we determined LRAT(E14L)'s enzymatic ...We would like to show you a description here but the site won't allow us.
Purpose: To report novel variants and characterize the phenotype associated with the autosomal recessive retinal dystrophy caused by mutations in the lecithin retinol acyltransferase (LRAT) gene. Methods: A total of 149 patients with Leber's congenital amaurosis (LCA) or early onset retinal dystrophy were screened for mutations in LCA-associated genes using an arrayed-primer extension (APEX ...The SKS shoots the same 7.62×39 round as the AK-47/AKM family of firearms, but is perhaps less widespread. Not to say that the SKS rifle isn't a reliable option, but it hasn't earned the same ...Defects in LRAT are a cause of Leber congenital amaurosis type 14 (LCA14) [MIM:613341]. It is a severe dystrophy of the retina, typically becoming evident in the first years of life. Visual function is usually poor and often accompanied by nystagmus, sluggish or near-absent pupillary responses, photophobia, high hyperopia and keratoconus.Mar 3, 2004 · The RPE of Lrat−/− mice is devoid of all-trans-retinol or all-trans-retinyl esters, photoreceptors have no functional rhodopsin, and electroretinogram (ERG) responses are highly attenuated. Lrat−/− mice are an important experimental model for human retinal dystrophies and for vitamin A deprivation.Lrat-Cre mice of a mixed background strain were provided by Dr. Robert Schwabe (Columbia University, New York, NY). Male mice were used exclusively for all experiments because of limitations of Lrat-Cre transgenic mice, which require that females with the cre transgene be used for all breeding because the males display mosaic germline …Lungs from Lrat +/+ and Lrat −/− mice were enzymatically digested and individual cells were subjected to FACS using a gating strategy to collect cells with high autofluorescence at λ = 455 nm ...The effective range of an SKS with 7.62x39mm ammo is typically around 400 meters. Can I use hollow point ammo in my SKS? Hollow point ammo can be used in SKS rifles, but it may not feed as reliably as full metal jacket rounds. What is the price range for SKS ammo? The price of SKS ammo can vary, but it typically ranges from $0.20 to $0.30 per ...Abstract. LRAT encodes lecithin retinol acyltransferase, which catalyzes the earlier reactions in the retinoid visual pathway in the retinal pigment epithelium (RPE). Recessive mutations in LRAT cause a spectrum of disease that ranges from Leber congenital amaurosis (LCA) to forms of “juvenile” or “early-onset” retinitis pigmentosa (RP ...
LRAT is encoded by this gene is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester, an essential reaction for the retinoid cycle in visual system and vitamin A status in liver. Mutations in this gene have been associated with early-onset severe retinal dystrophy. [provided by RefSeq]The SKS and AK series of rifles have always been popular arms and have vast numbers of owners that love them. This board is different from other forums in that it is geared more towards collectors, builders and shared research information of these immensely popular rifles. Give it a try as we think you will like the manner this board is run.Fluke Networks LRAT-1000 LinkRunner AT Network Auto-Tester is the fastest way to solve network connectivity problems. This rugged, handheld network tester takes the guesswork out of troubleshooting with its complete one-button AutoTest. AutoTest performs your required set of connectivity tests in seconds, enabling you to accurately and quickly identify and solve network problems. Key features ...These results indicate that the LRAT variant is the disease-causing factor in this family. LRAT is involved in the visual cycle and is expressed in multiple human tissues, including the retinal pigment epithelium and liver (MacDonald and Ong 1988). The protein (EC: 2.3.1.135) catalyzes the transfer of the acyl group from phosphatidylcholine to ...Abstract. Lecithin:retinol acyltransferase (LRAT) catalyzes the acyl transfer from the sn-1 position of phosphatidylcholine (PC) to all-trans-retinol, creating fatty acid retinyl esters (palmitoyl, stearoyl, and some unsaturated derivatives). In the eye, these retinyl esters are substrates for the 65 kDa retinoid isomerase (RPE65).Lecithin-retinol acyltransferase (LRAT), an enzyme present mainly in the retinal pigmented epithelial cells and liver, converts all-trans-retinol into all-trans-retinyl esters. In the retinal pigmented epithelium, LRAT plays a key role in the retinoid cycle, a two-cell recycling system that replenis …Klein Tools VDV500-705 Tone and Probe Tester and Tracer Kit New Sealed. $29.99. Trending at $37.95. Find many great new & used options and get the best deals for Fluke Networks LinkRunner AT 1000 Network Auto-Tester ( LRAT-1000) at the best online prices at eBay! Free shipping for many products!r/EscapefromTarkov. • 2 yr. ago. mikeyboy1681. Restrict high tier ammo that cannot be sold on flea market from being put into secure container! Suggestion. Just ran into an SKS …Lecithin:retinol acyltransferase (LRAT) is the major enzyme responsible for retinol esterification in the mammalian body. LRAT exhibits specific activity in the cells with active retinol metabolism where it converts retinols into retinyl esters, which represents the major storage form of retinol. Be …I recently spent some quality time with a 25-year-old Norinco-built “Chinese Type 56” SKS. The gun looked wonderful in the late-afternoon sunlight—the rifle’s full-length wooden stock and folding spike-style bayonet subtly undermining its Soviet-era utilitarian aesthetics. Although the parallel-to-the-barrel gas tube does resemble its ...LRAT, a dominant acyltransferase enzyme, catalyzes the formation of retinyl esters by transferring an acyl group from the sn-1 position of phosphatidylcholine (PC) to vitamin A 17. In contrast, HRASLS enzymes function as phospholipases A 1/2, cleaving PC and phosphatidylethanolamine (PE) to generate the corresponding lyso-phospholipids and free ...SKS should be a high damage, medium fire rate, high recoil, low capacity semi auto sniper basically. They could slightly nerf M39 damage and it would fit even better. While we’re …The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber ...The LinkRunner AT 2000 can also serve as a packet reflector at rates up to 1Gbps. LRAT-2000/LRAT-1000 comparison chart. Features. Videos. Accurately test and identify network connectivity problems with the 10 second AutoTest. Network connectivity test for twisted pair and fiber optic Ethernet links at 10, 100 and Gigabit rates.LRAT-2000-5PK Includes 5 LRAT-2000s and 5 WireView #2-6 cable ID sets. Note: Available only in the US, Canada and Europe. LRAT-2000-10PK Includes 11 LRAT-2000s and 11 WireView #2-6 cable ID sets. Note: Available only in the US, Canada and Europe. CIQ-GSV2 Includes CableIQ™ Qualification Tester, LinkRunner AT 1000, IntelliTone Pro 200 Probe ...Australian soldier looking into a Viet Cong tunnel discovered during Operation Crimp, Vietnam. An intense bombardment of the target region preceded the operation with the aim of neutralizing the strong defensive positions suspected to be guarding the headquarters. On the extremely cold morning of January 8, over 8,000 US and ANZAC troops were ...The enzyme responsible for conversion of all-trans-retinol into retinyl esters, the lecithin retinol acyltransferase (LRAT) has been characterized at the molecular level. The cDNA coding for this protein was cloned and its amino acid sequence deduced. LRAT is composed of a polypeptide of 230 amino acid residues with a calculated mass of 25.3 kDa.Wikipedia: The SKS self-loading carbine is a semi-automatic rifle designed by Soviet small arms designer Sergei Gavrilovich Simonov in 1945.The SKS was first...
Mods. Community content is available under CC BY-NC-SA unless otherwise noted. SKS CHOATE scope mount (CHOATE) is a mount in Escape from Tarkov. A mount for installing various sights on the SKS carbine. Manufactured by CHOATE.
Download scientific diagram | HCCs are not derived from HSCs. ( A - D ) Lrat-Cre Tg mice expressing the ZsGreen Cre reporter ( n = 4) were treated with DEN and 20 injections of CCl 4 for HCC ...
Today, a Chicom SKS will run you north of $300. Even adjusted for inflation, the price has more than doubled in those 25 years. "Surplus is drying up" Jacob Herman at Century Arms International told me when I inquired about the overseas availability of rifles such as the SKS. As fewer guns become available, prices will climb — thus, $300+ SKSs.One of the first things to look at when you want to know the production date of a Norinco SKS rifle is the symbol. It can identify the timeframe and factory location of the weapon's production. A diagram online will help match the SKS markings and worth of the rifle. The symbol indicates which factory the rifle came from and an estimate of the ...The SKS ( Russian: Самозарядный карабин системы Симонова, romanized : Samozaryadny karabin sistemy Simonova, lit. 'self-loading carbine of the Simonov system') is a semi-automatic rifle designed by …"A soviet carbine with significant armor penetration and reliable accuracy" The SKS is a soviet carbine meant to take the role of a semi-automatic rifle. Its addition as the first DMR to the dealer's stocks competes with the armory's FN-FAL with significant changes. It is viable at all ranges due to its moderately low recoil and tight spread combined with high damage. The SKS should ...r/SKS. • 1 yr. ago. ADMIN MOD. SKS Will Be Banned In WA. Just thought I would post a reminder about this thread from a while back. It's in the Washington State legislature as HB/SHB 1240, and has passed the House, and was on the order of consideration to pass the Senate this morning. It's probably too late, but if you feel like making an ...Thus, we investigated the contribution of vitamin A storage and transport to intestinal retinoid homeostasis and functionalities. We showed the occurrence of intestinal VAD in Lrat -/- Rbp -/- mice, demonstrating the critical role of both pathways in preserving gut retinoid homeostasis. Moreover, in the mutant colon, VAD resulted in compromised ...Last Updated: May 22, 2024 Kevin R. Comment (0) 29824 Views. The SKS rifle was an integral weapon during the height of the Cold War. The Soviet-manufactured assault rifle was a favorite among allied forces of the Eastern Bloc. It’s distinguished by a hinged, fixed 10-round magazine along with a folding bayonet.In 1988, evidence supporting LRAT function in the visual cycle was published by MacDonald et al. 25 In 2001, the LRAT gene, comprising of three exons, was mapped to chromosome 4q31.2. 26 The gene encodes a 230-amino acid enzyme that is expressed in several fetal and adult human tissues, including the retinal pigment epithelium (RPE) and liver. 27 …
imdb baldurt mobile insider codehomes for sale in stockton ca under dollar300 000state federal tug of war worksheet answers Sks lrat imagenes de buenos dias con movimiento y frases bonitas [email protected] & Mobile Support 1-888-750-7341 Domestic Sales 1-800-221-4729 International Sales 1-800-241-6883 Packages 1-800-800-8203 Representatives 1-800-323-8136 Assistance 1-404-209-7508. SKS Bottle and Packaging is a container and packaging supplier, consultant, and designer. We specialize in providing top-quality plastic bottles, glass bottles, plastic jars, glass jars, metal containers, and closures to meet your packaging needs. With our extensive online catalog, you'll find a wide range of containers and closures, curated to offer the best selection of products at .... fylm pwrn sksy Aim: The present study was undertaken to examine whether lecithin:retinol acyltransferase (LRAT), the physiological retinol esterification enzyme of the liver, is a potential and relevant tissue marker for HSC. Methods: An antibody specific to mouse and human LRAT was prepared based on the amino acid sequences. Antibodies to LRAT …LRATD2 (LRAT Domain Containing 2) is a Protein Coding gene. Diseases associated with LRATD2 include Breast Cancer. An important paralog of this gene is LRATD1. Additional gene information for LRATD2 Gene. HGNC (24166) NCBI Gene (157638) Ensembl (ENSG00000168672) OMIM® (609483) sksa arba10 day weather forecast for buffalo Lecithin retinol acyltransferase (LRAT) is a membrane-bound enzyme that catalyzes the transfer of an acyl group from the sn-1 position of lecithin to vitamin A, which generates all-trans-retinyl esters (tREs) in the liver, some extrahepatic tissues (such as the lung) and retinal pigmented epithelium. LRAT can also exchange palmitoyl groups ... swrakhy kwnopercent27reillypercent27s azle New Customers Can Take an Extra 30% off. There are a wide variety of options. Translated from the Russian by Maj. J. F. Gebhardt, The Official SKS Manual: Instructions for Use and Maintenance of the 7.62mm Simonov self-loading Carbine (SKS) (Boulder: Paladin Press, 1997), 42-44: So, just like the Mosin-Nagant, the unit's best shooter, the company commander, the armorer, and the soldier to be issued the thing in attendance--Here comes the SKS. The donor rifle was your average, used Chinese SKS, whith a bonus Choate mount. Great, I needed one for this build anyways, and I don't mind too much drilling holes in a receiver when it's already been tampered with. I got a Tapco stock for the pistol grip. My friend initially tried the feel of this stock on my son's Ruger ...Two Models: LRAT-2000 and LRAT-1000 LinkRunner AT is available in two models: LRAT-2000 and LRAT-1000. LinkRunner AT 2000 adds the following exclusive* features: Fiber support* TruePower™ PoE Power Test upto 30W* IPv6 support* - Reflector support* More reports: 50 instead of 10*